Abstract
Objective
The incidence of deterioration and associated characteristics are largely unknown
for children transported for admission from referring emergency departments (EDs)
to general inpatient units. This study describes this population and identifies associated
preadmission characteristics.
Methods
This single-center cohort study included children ≤ 18 years old transferred from
an ED and directly admitted to general inpatient units from 2016 to 2019. Deterioration
was defined as 1 or more of the following occurring within 24 hours of admission:
rapid response team activation, transfer to the intensive care unit (ICU), or cardiac
or respiratory arrest. ICU transfer was the secondary outcome. Logistic regression
was performed.
Results
One thousand nine hundred eighty-eight patients were included; the median age was
4.2 years, 53.9% were male, and 44.1% had respiratory diagnoses. Deterioration occurred
in 135 (6.8%) children overall and in 10.1% of children with respiratory complaints.
Deterioration was associated with ≥ 2 complex chronic conditions (adjusted odds ratio
[aOR] = 2.09; 95% confidence interval [CI], 1.04-4.19) and a longer stabilization
time (per 10 minutes) (aOR = 1.17; 95% CI, 1.01-1.36). ICU transfer was associated
with ≥ 2 complex chronic conditions (aOR = 2.33; 95% CI, 1.13-4.80), supplemental
oxygen via nasal cannula (aOR = 2.13; 95% CI, 1.18-3.85), and nebulizer treatment
(aOR = 2.77; 95% CI, 1.21-6.35).
Conclusion
Deterioration was experienced by 7% of children admitted to a general unit, with the
majority having respiratory complaints. Transport teams should consider the potential
for increased risk of deterioration among children with respiratory disease, multiple
complex chronic conditions, and a nasal cannula or nebulizer therapy. The clinical
significance of marginally longer stabilization times is unclear and warrants further
investigation.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Air Medical JournalAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Emergency department pediatric readiness and mortality in critically ill children.Pediatrics. 2019; 144e20190568
- Access to high pediatric-readiness emergency care in the United States.J Pediatr. 2018; 194 (e1): 5-232
- Trends in regionalization of emergency care for common pediatric conditions.Pediatrics. 2020; 145e20192989
- Characteristics and outcomes of emergency interhospital transfers from subacute to acute care for clinical deterioration.Int J Qual Health Care. 2019; 31: 117-124
- Risk factors for unplanned transfer to the intensive care unit after emergency department admission.Am J Emerg Med. 2017; 35: 1154-1158
- A critical analysis of unplanned ICU transfer within 48 hours from ED admission as a quality measure.Am J Emerg Med. 2016; 34: 1505-1510
- The use of a modified pediatric early warning score to assess stability of pediatric patients during transport.Pediatr Emerg Care. 2012; 28: 878-882
- Transport disposition using the Transport Risk Assessment in Pediatrics (TRAP) score.Prehosp Emerg Care. 2012; 16: 366-373
- Utilizing pediatric scoring systems to predict disposition during interfacility transport.Prehosp Emerg Care. 2019; 23: 249-253
- Assessment of interhospital transport care for pediatric patients.Clin Exp Pediatr. 2020; 63: 184-188
- Defining clinical deterioration.Resuscitation. 2013; 84: 1029-1034
- Pediatric Early Warning Score and unplanned readmission to the pediatric intensive care unit.J Crit Care. 2015; 30: 1090-1095
- Impact of rapid response system implementation on critical deterioration events in children.JAMA Pediatr. 2014; 168: 25-33
- Recognition of the critically ill patient and escalation of therapy.Anaesth Intensive Care. 2019; 20: 1-5
- Effect of transport team interventions on stabilization time in neonatal and pediatric interfacility transports.Air Med J. 2005; 24: 244-247
- Transport stabilization times for neonatal and pediatric patients prior to interfacility transfer.Pediatr Emerg Care. 1993; 9: 69-71
- Effect of patient- and team-related factors on stabilization time during pediatric intensive care transport.Pediatr Crit Care Med. 2010; 11: 451-456
- Development of heart and respiratory rate percentile curves for hospitalized children.Pediatrics. 2013; 131: e1150-e1157
- Heart rate and blood pressure centile curves and distributions by age of hospitalized critically ill children.Front Pediatr. 2017; 5: 52
- Coded Chief Complaints–automated analysis of free-text complaints.Acad Emerg Med. 2006; 13: 774-782
- Evaluation of a hospital admission prediction model adding coded chief complaint data using neural network methodology.Eur J Emerg Med. 2015; 22: 87-91
- Pediatric complex chronic conditions classification system version 2: updated for ICD-10 and complex medical technology dependence and transplantation.BMC Pediatr. 2014; 14: 199
- Pediatric acute respiratory distress syndrome: definition, incidence, and epidemiology: proceedings from the Pediatric Acute Lung Injury Consensus Conference.Pediatr Crit Care Med. 2015; 16: S23-S40
- Prediction of clinical deterioration after admission from the pediatric emergency department.Int Emerg Nurs. 2019; 43: 1-8
- Pediatric critical care resource use by children with medical complexity.J Pediatr. 2016; 177 (e1): 197-203
Article Info
Publication History
Published online: May 27, 2022
Footnotes
Thank you to Dr. Denise Goodman for her invaluable review of the manuscript.
Identification
Copyright
© 2022 Air Medical Journal Associates. Published by Elsevier Inc. All rights reserved.