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Editors' note: This article is the sixth in a multipart series designed to improve the knowledge base of readers, particularly novices, in the area of clinical research. A better understanding of these principles should help in reading and understanding the application of published studies. It should also help those involved in beginning their own research projects.
1 Cheryl Bagley Thompson, PhD, RN, is an assistant dean of informatics and learning technologies and director of the health informatics program at the University of Nebraska Medical Center, College of Nursing, in Omaha, Nebraska.
2 Edward A. Panacek, MD, MPH, is professor of emergency medicine and clinical toxicology and director of clinical trials at the UC Davis Medical Center in Sacramento, California.
